冯陈晨，博士，副教授，365全球官方网站教师，衡阳市高层次人才。生物医学工程专业，研究领域为“重大疾病基因调控网络的构建与分析”。研究方向主要包括：心血管、癌症等重大疾病中基因调控网络的构建与分析方法研究、转录因子识别算法研究、通路识别及其功能分析。主持国家自然科学基金青年项目、湖南省自然科学基金面上项目、湖南省教育厅优秀青年项目、黑龙江省自然科学基金优秀青年项目、伍连德青年基金等多项科研项目和课题，以第一作者在《Nucleic Acids Research》、《Molecular Therapy Nucleic Acids》等杂志发表SCI论文11篇。
近五年主持或参加的项目/课题
(1) 国家自然科学基金委员会, 青年科学基金项目（C类）[原青年科学基金项目], 62001145, 整合转录因子调控图谱的癌症高风险代谢通路异常区域识别, 2021-01-01 至 2023-12-31, 24万元, 结题, 主持
(2) 湖南省科学技术厅, 湖南省自然科学基金面上项目, 2025JJ50105, 融合多组学数据的乳腺癌关键转录调控子识别及调控网络分析方法研究, 2025-01 至 2027-12, 5万元, 在研, 主持
(3) 湖南省教育厅, 优秀青年项目, 24B0417, 结肠癌单细胞ATAC-seq转录调控网络的构建与分析, 2025-01 至 2027-12, 6万元, 在研, 主持
(4) 黑龙江省自然科学基金, 杰出青年项目, JQ2020C004, 重大疾病中超级增强子的上游信号通路识别及调控机制研究, 2020-07 至 2023-12, 50万元, 结题, 参与
代表性研究成果
[1] Song S#, Liu L#, Feng C#, Xie L#, Zhang G, Zhang Y, Gao Y, Yin M, Tang X, Pei W, Song C*, Liu R*, Li C*. SEdb 3.0: a comprehensive super-enhancer database across multiple species. Nucleic Acids Res. 2026 Jan 6;54(D1):D322-D333.
[2] Yin M#, Feng C#, Yu Z#, Zhang Y#, Li Y, Wang X, Song C, Guo M*, Li C*. sc2GWAS: a comprehensive platform linking single cell and GWAS traits of human. Nucleic Acids Res. 2025 Jan 6;53(D1):D1151-D1161.
[3] Feng C#, Song C#, Song S#, Zhang G, Yin M, Zhang Y, Qian F, Wang Q, Guo M*, Li C*. KnockTF 2.0: a comprehensive gene expression profile database with knockdown/knockout of transcription (co-)factors in multiple species. Nucleic Acids Res. 2024 Jan 5;52(D1):D183-D193.
[4] Song C#, Zhang G#, Mu X#, Feng C#, Zhang Q, Song S, Zhang Y, Yin M, Zhang H, Tang H*, Li C*. eRNAbase: a comprehensive database for decoding the regulatory eRNAs in human and mouse. Nucleic Acids Res. 2024 Jan 5;52(D1):D81-D91.
[5] Feng C#, Song C#, Jiang Y#, Zhao J#, Zhang J, Wang Y, Yin M, Zhu J, Ai B, Wang Q, Qian F, Zhang Y, Shang D, Liu J, Li C*. Landscape and significance of human super enhancer-driven core transcription regulatory circuitry. Mol Ther Nucleic Acids. 2023 Mar 24;32:385-401.
[6] Gao Y#, Feng C#, Zhang Y#, Song C#, Chen J, Li Y, Wei L, Qian F, Ai B, Liu Y, Zhu J, Su X*, Li C*, Wang Q*. TRmir: A Comprehensive Resource for Human Transcriptional Regulatory Information of MiRNAs. Front Genet. 2022 Feb 4;13:808950.
[7] Feng C#, Song C#, Liu Y#, Qian F, Gao Y, Ning Z, Wang Q, Jiang Y, Li Y, Li M, Chen J, Zhang J*, Li C*. KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors. Nucleic Acids Res. 2020 Jan 8;48(D1):D93-D100.
[8] Feng C#, Song C#, Ning Z#, Ai B, Wang Q, Xu Y, Li M, Bai X, Zhao J, Liu Y, Li X, Zhang J*, Li C*. ce-Subpathway: Identification of ceRNA-mediated subpathways via joint power of ceRNAs and pathway topologies. J Cell Mol Med. 2019 Feb;23(2):967-984.
[9] Ning Z#, Feng C#, Song C#, Liu W, Shang D, Li M, Wang Q, Zhao J, Liu Y, Chen J, Yu X*, Zhang J*, Li C*. Topologically inferring active miRNA-mediated subpathways toward precise cancer classification by directed random walk. Mol Oncol. 2019 Oct;13(10):2211-2226.
[10] Zhang J#, Feng C#, Song C#, Ai B, Bai X, Liu Y, Li X, Zhao J, Shi S, Chen X, Su X*, Li C*. Identification and analysis of a key long non-coding RNAs (lncRNAs)-associated module reveal functional lncRNAs in cardiac hypertrophy. J Cell Mol Med. 2018 Feb;22(2):892-903.
[11] Feng C#, Zhang J#, Li X#, Ai B, Han J, Wang Q, Wei T, Xu Y, Li M, Li S, Song C, Li C*. Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways. Sci Rep. 2016 Sep 14;6:33262.
